The XMD ToolBox is the Ultimate ZBrush Organizer. With its simple interface, the ToolBox will significantly speed up your workflow.
Be sure to check out the Getting Started guide for the Installation & Activation steps.
Once you have the ToolBox installed and activated you can check out the User's Guide for information on every feature inside of the ToolBox as well as a User Interface breakdown.
If you get stuck there is also a detailed reference guide with information on every button and toggle in the ToolBox.